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Neutropenia means a low neutrophil count in circulating white blood cells and is defined as:

• A neutrophil count of ≤0.5 x 10⁹/L
• Temperature ≥38.5^°C OR two consecutive readings of ≥38.0^°C for 2 hours

Causes

Neutropenia means a low neutrophil count in circulating white blood cells and is defined as:

• A neutrophil count of ≤0.5 x 10⁹/L
• Temperature ≥38.5^°C OR two consecutive readings of ≥38.0^°C for 2 hours

Causes

There are a variety of causes, including:

• Bone marrow infiltration with malignancy
• Chemotherapy (cytotoxics and immunosuppressants)
• Infections, e.g. HIV
• Congenital reasons
• Thyroid dysfunction
• Autoimmune disease
• Vitamin B12 deficiency